Melton residents can expect delays along Exford Road from Friday, February 14 to Friday, March 7.
The works, which are part of the level crossing removal project, involve relocating gas mains under Exford Road.
The roadworks will include digging trenches on either side of the level crossing to install new underground gas pipes.
From Friday, February 14 at 9pm to Monday, February 17 at 5am, Exford Road will be closed at the level crossing, but a detour through Coburns Road will be open. Creek Street access will be maintained.
It will then close from Friday, February 21 at 9am to Monday, February 24 at 5am.
From Monday, February 17 to Friday, March 7, there will be intermittent southbound lane closures from 9am to 3pm.
Access to businesses and homes will be maintained, but motorists will need extra time when travelling in the area of construction.
Impacted residents will be notified before any night construction works.